Lichen Planus
Chronic inflammatory disease affecting skin
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| Term | Definition |
|---|---|
| Lichen Planus | Chronic inflammatory disease affecting skin |
| Skin Lesion Features | 6P Plain topped Purple Polygonal Pruritic Papules Plaques |
| Nail Changes | • Thinning (m/c) • Pup tent sign • Dorsal Pterygium (m sp) • Tracheonychia |
| Oral Lesion | Reticular white Wickham striae; erosive/ulcerative lesions possible |
| Pathology | Saw-tooth appearance of rete ridges; band-like lymphocytic infiltrate; Civatte bodies |
| Classic Sites | Flexor wrists |
| Associated Infection | Hepatitis C |
| Variants | Hypertrophic (thick plaques) |
| Diagnosis | Clinical Biopsy for confirmation (atypical/severe cases) |
| Malignant Potential | Oral erosive lichen planus has low but present risk for malignant transformation |
| Management | Topical steroids first-line; oral steroids/immunosuppressants/calcineurin inhibitors if severe |
| Koebner Phenomenon | Lesion formation at sites of trauma |
| Drug-induced LP | Biopsy may show eosinophils |
| Differential Diagnosis | Psoriasis |
| Complications | Post-inflammatory hyperpigmentation |