Neural Anatomy and Neural Plasticity

Created by Amaya Virden

MRI
Provides detailed images of brain structure; used in diagnosis, development, and mapping brain regions

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TermDefinition
MRI
Provides detailed images of brain structure; used in diagnosis, development, and mapping brain regions
fMRI
Tracks blood-flow changes to identify brain activity during tasks or mental processes
PET
Uses radioactive tracers to show metabolism, chemistry, and brain function
TMS (Transcranial Magnetic Stimulation)
Uses magnetic pulses to temporarily modulate activity in targeted brain regions
Intracranial EEG (iEEG
Records electrical activity directly from the brain, often for epilepsy mapping and research
Genetic tools and computational modeling
Help identify biological mechanisms and patterns in brain data.
Molecular imaging
Visualizes cellular and molecular processes in the brain.
Central Nervous System
a.The Brain (Brain Stem, Cerebellum, Cerebrum) b.Spinal Cord integrates internal sensations
Peripheral Nervous System
a.Sympathetic b.Parasympathetic Systems
Central Nervous System
The central nervous system (CNS) consists of the brain and spinal cord and serves as the body's primary information-processing and communication network. It receives information from the senses, interprets that information, and coordinates thoughts, emotions, and behaviors. Trauma can significantly affect the functioning of the CNS, leading to heightened reactivity, difficulty regulating emotions, and changes in attention, memory, and perception.
Autonomic Nervous System
consists of the parasympathetic nervous system and sympathetic nervous system.
Sympathetic Nervous System
prepares the body to respond to perceived danger by increasing alertness, heart rate, and mobilizing energy for action. Individuals who have experienced trauma often spend excessive time in sympathetic activation, leading to chronic anxiety, hypervigilance, and difficulty feeling safe.
Parasympathetic nervous system
helps the body rest, recover, and return to a state of balance and safety. A central goal of trauma-informed clinical practice is helping clients strengthen their capacity to access parasympathetic states that support regulation, connection, healing, and resilience
Triune Brain Model
model that describes the brain as three interconnected systems that developed over the course of evolution
Brainstem
helps regulate basic survival functions
limbic system
involved in emotions and relationships
cortex
which supports thinking, reasoning, and self-awareness
Lizard brain
brain stem & cerebellum fight or flight autopilot
Mammal brain
Limbic system Emotions , memories, habits Decisions
Human brain
neocortex language , abstract , imagination , consciousness reasons, rationalizes
Brainstem (lower brain )
1.) Regulates vital body functions: breathing, heart rate, other automatic functions 2. The most ancient part of the brain (reptilian) 3. Vagus nerve connects the medulla in the brainstem to the stomach, lungs, heart; & is associated with parasympathetic nervous system
Vagus nerve
connects the medulla in the brainstem to the stomach, lungs, heart; & is associated with parasympathetic nervous system
Limbic system (midbrain )
Thalamus , amygdala ,hippocampus, hypothalamus
Thalamus
gateway for sensory information
Amygdala
emotions
Hippocampus
learning and memory
Hypothalamus
regulates automatic functions
Pre-frontal cortex
1. Executive functions 2. Cognition 3. Planning 4. Decision making 5. Sequencing 6. Goal-directed behavior 7. Independent thinking 8. Personality characteristics 9. Socially appropriate behavior
Neuron
1. A neuron is a specialized nerve cell unique to the Central Nervous System and serves as the basic building block the human brain. 2. Neurons receive, process, and transmit information through electrical and chemical signals. 3. They communicate with other neurons to coordinate body functions and behavior. 4. A typical neuron consists of a cell body, dendrites that receive messages, and axon that sends messages
Anatomy of a Neuron
dendrites, cell body (soma), nucleus, axon, myelin sheath
Dendrites
receive incoming information
Cell Body (Soma)
integrates information
Axon
send messages to other neurons through electrical impulses
Myelin Sheath
speeds signal transmission
Neural pathways
are a string of neurons transmitting signals between brain regions that allow information to travel throughout the brain and nervous system.
Synaptic gap
is the gap between one neuron’s dendrite and another's neurons axon
Neural transmitters
chemical molecule messengers that allow neurons to communicate with one another across these synaptic gap. When an electrical signal reaches the end of a neuron, neurotransmitters are released and travel to a connecting neurons.
Dopamine
involved in motivation, reward, pleasure, and movement
Serotonin
helps regulate mood, sleep, appetite, and overall well-being.
Norepinephrine
plays a role in alertness, attention, and the body's stress response
GABA
the brain's primary calming neurotransmitter; helps reduce anxiety and overstimulation.
Neural plasticity
is the brain’s ability to change its structure and function in response to experience or learning through the strengthening or weakening of neural connections. The brain continuously changes its synaptic interconnections in response to experience known as neural plasticity. Repeated experiences influence the strength of these synaptic connections. Intentional thought and behavior can actively reshape neural architecture
Hebb's rule
When neurons fire together repeatedly, these neurons become wired together – what fires together wires together. This firing and wiring together strengthens, known as LTP (long term potentiation). When neurons stop firing together bonds weaken known as LTD (long term depotentiation).