Chapter 6: Overview of the Cell

Created by Sofia Hawkins

Four things every cell common to all types
Cell membrane, cytosol, chromosomes, ribosomes

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TermDefinition
Four things every cell common to all types
Cell membrane, cytosol, chromosomes, ribosomes
Eukaryotic cell compartmentalization
Organelles create localized environments, allowing incompatible processes to occur within the same cell
Microscopes
Instruments used to understand and study cells where visible light is passed through a specimen and then through glass lenses
Magnification
Ratio of image size to real size
Resolution
Clarity of the image
Contrast
Visible difference in brightness
Scanning electron microscopes (SEMs)
Microscopes that focus a beam of electrons onto the surface of a specimen, providing a 3-D view
Transmission electron microscopes (TEMs)
Microscopes that focus a beam of electrons through a specimen to study internal cell structure
Prokaryotic cells
DNA sits unbound in a region called the nucleoid with no membrane-bound organelles, and cytoplasm is bound only by the plasma membrane
Eukaryotic cells
DNA is enclosed in a nucleus, and cells contain membrane-bound organelles with cytoplasm in the region between the plasma membrane and nucleus
Surface area-to-volume ratio
Ratio that helps set limits on how large a cell can be as it increases in size
Nucleus
The cell's info center, enclosed by a nuclear envelope (double membrane) containing nuclear pores that regulate what enters/exits
Nuclear lamina
Made of protein, sits on the nuclear side of the envelope and helps maintain the cell's shape; evidence also points to a nuclear matrix (framework of protein fibers inside the nucleus)
Chromatin
DNA organized into discrete units called chromosomes; each contains one DNA molecule associated with proteins that condenses further during cell division
Nucleolus
Site inside the nucleus where ribosomal RNA (rRNA) is synthesized
Free ribosomes
Complexes of ribosomal RNA and protein that build proteins in the cytosol
Bound ribosomes
Ribosomes on the outside of the ER or nuclear envelope that build proteins
Endomembrane system
System that regulates protein traffic and performs metabolic functions, consisting of the nuclear envelope, endoplasmic reticulum (ER), Golgi apparatus, lysosomes, vacuoles, and the plasma membrane
Smooth ER
Lacks ribosomes; synthesizes lipids, detoxifies drugs/poisons, and stores calcium ions
Rough ER
Studded with ribosomes; produces glycoproteins and transport vesicles, and is considered the cell's "membrane factory"
Golgi apparatus
The cell's shipping/receiving center made of flattened membranous sacs called cisternae; modifies products of the ER, manufactures certain macromolecules, and sorts/packages materials into transport vesicles
Lysosomes
Membranous sacs of hydrolytic enzymes that digest macromolecules; have an acidic internal environment, are made by the rough ER, sent to the Golgi, and may bud from the trans face
Phagocytosis
Process where lysosomes fuse with a food vacuole and digest its contents
Autophagy
Process where lysosomes recycle the cell's own organelles and macromolecules
Contractile vacuoles
Large vesicles derived from the ER and Golgi that pump excess water out of freshwater protist cells
Central vacuoles
Found in mature plant cells; contain sap and store ions like potassium and chloride
Mitochondria
Found in nearly all eukaryotic cells and are the site of cellular respiration
Chloroplasts
Found only in plants/algae and are the site of photosynthesis
Cristae
Folds in a mitochondrion's inner membrane that provide a large surface area for enzymes making ATP
Mitochondrial matrix
Space inside the mitochondrial inner membrane containing enzymes
Thylakoids
Membranous sacs inside a chloroplast stacked into a granum, containing chlorophyll in its internal fluid (the stroma)
Peroxisomes
Specialized metabolic compartments that use oxygen to break fatty acids into smaller molecules and form hydrogen peroxide as a byproduct; in liver cells, they detoxify alcohol and other harmful compounds
Glyoxysomes
Specialized peroxisomes in plant seeds that convert fatty acids into sugar for the seedling
Endosymbiont theory
Theory proposing that mitochondria and chloroplasts evolved from free-living prokaryotes engulfed by an early ancestor of eukaryotic cells (evidence includes a double membrane, free ribosomes, and circular DNA molecules)
Cytoskeleton
Network of fibers built from three structures: microtubules (thickest), intermediate filaments, and microfilaments (thinnest, also called actin filaments)
Motor proteins
Proteins that use "feet" and ATP to let vesicles and organelles travel along cytoskeletal tracks
Microtubules
Hollow rods built of tubulin dimers that shape the cell, guide organelle movement, and separate chromosomes during cell division; in animal cells they grow out from the centrosome
Cilia and flagella
Extensions of the plasma membrane used for locomotion, anchored by a basal body; dynein drives their bending movement
Microfilaments (actin filaments)
Form a cortex just inside the plasma membrane to support cell shape and make up the core of microvilli in intestinal cells
Pseudopodia
Cellular extensions used by cells to crawl, driven by the motor protein myosin and actin
Cytoplasmic streaming
Circular flow of cytoplasm in plant cells driven by actin-protein interactions
Intermediate filaments
Sized between microtubules and microfilaments; the most permanent cytoskeletal fixtures that help support cell shape and fix organelles in place
Plant cell wall
Proteins and cellulose fibers embedded to protect plant cells, maintain shape, and prevent excessive water uptake (includes primary wall, middle lamella with pectin, and secondary wall)
Extracellular Matrix (ECM)
Elaborate matrix in animal cells made of glycoproteins like collagen, proteoglycans, and fibronectin, which bind receptor proteins called integrins
Tight junctions
Animal cell junctions that press neighboring membranes together to prevent leakage of extracellular fluid
Desmosomes
Anchoring junctions that fasten animal cells into strong sheets
Gap junctions
Communicating junctions that provide cytoplasmic channels between adjacent animal cells
Plasmodesmata
Channels in plant cells that connect adjacent cells, letting water, small solutes, and sometimes proteins/RNA pass between them
Four things every cell common to all types
Cell membrane, cytosol, chromosomes, ribosomes
Eukaryotic cell compartmentalization
Organelles create localized environments, allowing incompatible processes to occur within the same cell
Microscopes
Instruments used to understand and study cells where visible light is passed through a specimen and then through glass lenses
Magnification
Ratio of image size to real size
Resolution
Clarity of the image
Contrast
Visible difference in brightness
Scanning electron microscopes (SEMs)
Microscopes that focus a beam of electrons onto the surface of a specimen, providing a 3-D view
Transmission electron microscopes (TEMs)
Microscopes that focus a beam of electrons through a specimen to study internal cell structure
Prokaryotic cells
DNA sits unbound in a region called the nucleoid with no membrane-bound organelles, and cytoplasm is bound only by the plasma membrane
Eukaryotic cells
DNA is enclosed in a nucleus, and cells contain membrane-bound organelles with cytoplasm in the region between the plasma membrane and nucleus
Surface area-to-volume ratio
Ratio that helps set limits on how large a cell can be as it increases in size
Nucleus
The cell's info center, enclosed by a nuclear envelope (double membrane) containing nuclear pores that regulate what enters/exits
Nuclear lamina
Made of protein, sits on the nuclear side of the envelope and helps maintain the cell's shape; evidence also points to a nuclear matrix (framework of protein fibers inside the nucleus)
Chromatin
DNA organized into discrete units called chromosomes; each contains one DNA molecule associated with proteins that condenses further during cell division
Nucleolus
Site inside the nucleus where ribosomal RNA (rRNA) is synthesized
Free ribosomes
Complexes of ribosomal RNA and protein that build proteins in the cytosol
Bound ribosomes
Ribosomes on the outside of the ER or nuclear envelope that build proteins
Endomembrane system
System that regulates protein traffic and performs metabolic functions, consisting of the nuclear envelope, endoplasmic reticulum (ER), Golgi apparatus, lysosomes, vacuoles, and the plasma membrane
Smooth ER
Lacks ribosomes; synthesizes lipids, detoxifies drugs/poisons, and stores calcium ions
Rough ER
Studded with ribosomes; produces glycoproteins and transport vesicles, and is considered the cell's "membrane factory"
Golgi apparatus
The cell's shipping/receiving center made of flattened membranous sacs called cisternae; modifies products of the ER, manufactures certain macromolecules, and sorts/packages materials into transport vesicles
Lysosomes
Membranous sacs of hydrolytic enzymes that digest macromolecules; have an acidic internal environment, are made by the rough ER, sent to the Golgi, and may bud from the trans face
Phagocytosis
Process where lysosomes fuse with a food vacuole and digest its contents
Autophagy
Process where lysosomes recycle the cell's own organelles and macromolecules
Contractile vacuoles
Large vesicles derived from the ER and Golgi that pump excess water out of freshwater protist cells
Central vacuoles
Found in mature plant cells; contain sap and store ions like potassium and chloride
Mitochondria
Found in nearly all eukaryotic cells and are the site of cellular respiration
Chloroplasts
Found only in plants/algae and are the site of photosynthesis
Cristae
Folds in a mitochondrion's inner membrane that provide a large surface area for enzymes making ATP
Mitochondrial matrix
Space inside the mitochondrial inner membrane containing enzymes
Thylakoids
Membranous sacs inside a chloroplast stacked into a granum, containing chlorophyll in its internal fluid (the stroma)
Peroxisomes
Specialized metabolic compartments that use oxygen to break fatty acids into smaller molecules and form hydrogen peroxide as a byproduct; in liver cells, they detoxify alcohol and other harmful compounds
Glyoxysomes
Specialized peroxisomes in plant seeds that convert fatty acids into sugar for the seedling
Endosymbiont theory
Theory proposing that mitochondria and chloroplasts evolved from free-living prokaryotes engulfed by an early ancestor of eukaryotic cells (evidence includes a double membrane, free ribosomes, and circular DNA molecules)
Cytoskeleton
Network of fibers built from three structures: microtubules (thickest), intermediate filaments, and microfilaments (thinnest, also called actin filaments)
Motor proteins
Proteins that use "feet" and ATP to let vesicles and organelles travel along cytoskeletal tracks
Microtubules
Hollow rods built of tubulin dimers that shape the cell, guide organelle movement, and separate chromosomes during cell division; in animal cells they grow out from the centrosome
Cilia and flagella
Extensions of the plasma membrane used for locomotion, anchored by a basal body; dynein drives their bending movement
Microfilaments (actin filaments)
Form a cortex just inside the plasma membrane to support cell shape and make up the core of microvilli in intestinal cells
Pseudopodia
Cellular extensions used by cells to crawl, driven by the motor protein myosin and actin
Cytoplasmic streaming
Circular flow of cytoplasm in plant cells driven by actin-protein interactions
Intermediate filaments
Sized between microtubules and microfilaments; the most permanent cytoskeletal fixtures that help support cell shape and fix organelles in place
Plant cell wall
Proteins and cellulose fibers embedded to protect plant cells, maintain shape, and prevent excessive water uptake (includes primary wall, middle lamella with pectin, and secondary wall)
Extracellular Matrix (ECM)
Elaborate matrix in animal cells made of glycoproteins like collagen, proteoglycans, and fibronectin, which bind receptor proteins called integrins
Tight junctions
Animal cell junctions that press neighboring membranes together to prevent leakage of extracellular fluid
Desmosomes
Anchoring junctions that fasten animal cells into strong sheets
Gap junctions
Communicating junctions that provide cytoplasmic channels between adjacent animal cells
Plasmodesmata
Channels in plant cells that connect adjacent cells, letting water, small solutes, and sometimes proteins/RNA pass between them
Path of a protein for secretion
Ribosome (Rough ER) -> Golgi Apparatus -> Transport vesicle -> Secretory vesicle -> Plasma membrane -> Exocytosis
Endosymbiont Theory evidence
1. Free ribosomes, 2. Double membrane, 3. Circular DNA molecules
Why cells are compartmentalized
Organelles create localized environments, allowing incompatible processes to occur simultaneously within the same cell
Cellular components used when a cell crawls
Microfilaments (actin) and myosin motor proteins extending pseudopodia
Plant cell structural support under stress
Relies on the cell wall made of cellulose
Animal cell structural support under stress
Relies on the extracellular matrix (ECM), a flexible network of proteins and carbohydrates like collagen