Nucleotides and Nucleic Acids - do on 17/06
Created by Fortune Teibowei
Summarise the process of DNA replication.
- DNA helicase breaks hydrogen bonds between base pairs forming two strands
- each original strand acts as a template strand
- free DNA nucleotides pair with exposed bases on the template strands via complementary base pairing
- DNA polymerase catalyses the formation of phosphodiester bonds between adjacent nucleotides forming the sugar phosphate backbones
- hydrogen bonds form between complementary bases
- two identical DNA molecules are produced
| Term | Definition |
|---|---|
Summarise the process of DNA replication. | - DNA helicase breaks hydrogen bonds between base pairs forming two strands
- each original strand acts as a template strand
- free DNA nucleotides pair with exposed bases on the template strands via complementary base pairing
- DNA polymerase catalyses the formation of phosphodiester bonds between adjacent nucleotides forming the sugar phosphate backbones
- hydrogen bonds form between complementary bases
- two identical DNA molecules are produced |
Summarise the process of protein synthesis. | Transcription:
- DNA helicase breaks hydrogen bonds between base pairs forming two strands
- one of the original strands acts as a template strans
- free RNA nucleotides pair with exposed bases on the template strands via complementary base pairing
- RNA polymerase catalyses the formation of phosphodiester bonds between adjacent nucleotides forming the sugar phosphate backbone of the mRNA molecule
- the mRNA molecule detaches from the DNA and leaves the nucleus through a nuclear pore to go to the ribosome for translation
Translation:
- ribosome attaches to mRNA
- a tRNA molecule arrives carrying an amino acid and its anticodon pairs with the complementary codon on the mRNA
- this happens again and the amino acids attached to the two tRNA molecules join via a peptide bond
- the tRNA molecules detach from the amino acids
- this process is repeated until a stop codon is reached on the mRNA |
What are the features of the genetic code and what do they mean? | non-overlapping - triplets don't share bases
degenerate - more than one triplet codes for the same amino acid (reduces the effect of mutations) |