Q2 - T or F: NE is released by axon terminals in the central nervous system and in the peripheral nervous system, and directly into the bloodstream by the adrenal medulla

TRUE

Q2 - Which of the following 5-HT receptor subtypes functions as both a autoreceptor (i.e., reducing 5-HT release) and as a heteroreceptor (e.g., reducing dopamine release)?

5-HT1B

Q2 - Which of the following drugs can be used to treat opioid (e.g., heroin) withdrawal?

Clonidine

Q2 - Which of the following 5-HT receptor subtypes is NOT a G protein-coupled receptor, but rather functions as a ligand-gated ion channel?

5-HT3

Q2 - Which of the following prevents a significant increase in brain levels of serotonin after taking the dietary supplement tryptophan?

Blood brain barrier

Q2 - Which of the following breaks down (metabolizes) Achetylcholine in the synapse?

Acetylecholinesterase (AChE)

Q2 - Which of the following drugs is used to treat migraine headahces?

Zolmitriptan

Q2 - Which of the following transporters is responsible for packaging dopamine & norepinephrine into synaptic vesicles in neurons (i.e., the brain)?

VMAT2

Q2 - Which of the following receptors is NOT an autoreceptor?

B2 - norepinephrine

Q2 - Which of the following GABA receptor subtypes is a G-protein coupled receptor?

GABA (low B)

Q2 - Which of the following drugs are used to treat schizophrenia?

D2 antagonist

Q2 - Which of the following protein kinases is activated by group 1 mGluR receptors?

PKC

Q2 - Which of the following receptors does the excitatory neurotransmitter glutamate bind to?

All of above: NMDA; mGluR1; mGluR8; AMPA

Q2 - Which of the following drugs does NOT have a unique binding site on GABAA receptors?

PCP

Q2 - Which of the following receptors has it's ion channel blocked by Mg2+, and thus requires membrane depolarization to open the ion channel?

NMDA

Q2 - Which of the following inhibits cholinergic release throughout the CNS & PNS, potentially leading to paralysis and death by asphyxiation?

Botulinum toxin

Q2 - Which of the following inhibits cholinergic release throughout the PNS, potentially leading to severe muscle contractions?

Black widow spider venom