The Body-Cells & Molecules

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Type of nucleic acid and functions
DNA:organised into chromosomes which must replicate and divide during cell division.Its the genetic code contains both coding and non-coding regions RNA: Transfer,Messenger,Ribosomal responsible to make amino acid

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TermDefinition
Type of nucleic acid and functions
DNA:organised into chromosomes which must replicate and divide during cell division.Its the genetic code contains both coding and non-coding regions RNA: Transfer,Messenger,Ribosomal responsible to make amino acid
Main process in protein synthesis
Transcription and translation
Describe the primary structure of protein
A polypeptide chain made up of amino acids joining via peptide bond through condensation reaction. Determines the function and structure of protein
Describe the secondary structure of protein
Folding of the polypeptide chain forming either alpha helix or beta pleated sheets. This is due to hydrogen bonds between C-O
Describe the tertiary structure of protein
Three-dimensional folding pattern of the polypeptide chain via ionic bond, hydrogen bonds and disulphide bridges
Describe the quaternary structure
More than one polypeptide chain join together via hydrogen bonds forming a more complex structure
What type of complexes can protein form
Structural (eg.muscle), Enzymes, Cell signalling (eg. receptors, ion channels, hormones, antibodies)
What is an enzyme and its function
Its a biological catalyst where substrates binds to be converted into its product. Key for: metabolism, detoxification, energy
What is ATP ( structure + function)
Adenine base with 3 phosphates. Facilitates many cellular processes by providing energy. Key for energy-hydrolysis, ATPase
Type of lipids
Triglycerides, Phospholipids, Steroids and waxes
Where does lipids come from
Dietary, many from excess carbohydrates
What are the functions of lipids
Cell membrane, Energy storage, Signalling properties
What are the type of Carbohydrate and function
Glucose to glycogen or fat. Main energy source
What is cell membrane (structure + functions)
Made of phospholipids. Control what ion/molecule is able to get in and out (semi permeable). Contains transporters, receptors and channels responsible for detecting changes in environment/signals
What is contained in the nucleus and its functions
Contains DNA ( transcribed to RNA for protein synthesis). Respond to signals to make more/less of certain proteins. Its divided during semi-conservative replication
Where is endoplasmic reticulum is located and type
Rough and smooth, ribosomes, Sarcoplasmic reticulum (muscles) stores calcium
Function of golgi apparatus
Receives proteins from ER where it modifies protein where its then packaged into vesicles to transport around the cell
Type of Vesicles
Exocytotic (immediate release) , Secretory (stored until signalled to release) ,Lysosomal (lysosomes)
What does lysosomes contain and function
Contain degradative enzymes. Responsible for the breakdown of polymers eg. DNA/RNA, polysaccharides
What does peroxisomes contain and function
Contain oxidases. Breakdown fatty acids and toxic compounds
Where is cytoskeleton located and its function
Attached to plasma membrane. Provides a framework for cellular organisation. Dynamic
Function of mitochondria, why is it unique
Generated ATP from oxidation of glucose and fatty acids. Contains mitochondrial DNA
Function of stem cell
Self renewal. It undergoes differentiation, tissue specific
What stem cell can form all cell types, including extra-embryonic tissue. Example
Totipotent, zygote
Which stem cell can form all body cell types but not the placenta. Example
Pluripotent cell, embryonic stem cell
Which stem cell can form several related cell types within one tissue family. Example
Multipotent cell, Hematopoietic stem cell (RBS,WBC,Platelets)
Which stem cell is more specialized than a multipotent stem cell and give rise to a limited number of cell types
Progenitor cell- limited differentiation potential, shorter self-renewal capacity
What is precursor cell
A nearly differentiated cell committed to becoming a specific mature cell type
What is a somatic cell
A fully differentiated mature body cell
Order from most potent to least potent
Totipotent, Pluripotent, Multipotent, Progenitor, Precursor, Somatic
Importance of diversity of cell types
Specific cells and tissue have molecular signatures (ie. receptors, ion channels). This is great for drug discovery as its specific