History (first test)

Created by sadie welcome

What is the Ebers Papyrus?
Egyptian text with 800 prescriptions & 700+ substances

1/43

TermDefinition
What is the Ebers Papyrus?
Egyptian text with 800 prescriptions & 700+ substances
What civilization first recorded pharmacy practices?
Babylonia
Who wrote the Pen T-Sao?
Shen Nung
How many drugs were recorded in Pen T-Sao?
365
Who systematized pharmacy?
Galen
What is Galenical pharmacy?
Precise compounding of drugs
How long did Galen's influence last?
1,500 years
Who wrote the Canon of Medicine?
Ibn Sina (Avicenna)
What major professional change occurred?
Separation of pharmacy and medicine
What major professional change occurred during Avicenna's era?
Separation of pharmacy and medicine
Who rejected humoral theory?
Paracelsus
What is chemotherapy?
Targeted chemical treatment of disease
What is chemotherapy originally?
Targeted chemical treatment of disease
Who isolated morphine?
Friedrich Sertürner
Why was morphine isolation important?
Proved drugs are discrete chemical entities
Who introduced the "magic bullet" concept?
Paul Ehrlich
What was Salvarsan used to treat?
Syphilis
Who enabled mass production of penicillin?
Florey and Chain
First genetically engineered drug?
Recombinant human insulin (1982)
What innovation did recombinant human insulin represent?
Shift from chemical synthesis to biological engineering
What is pharmacogenomics?
Drug therapy based on genetics
Examples of modern biologics
Monoclonal antibodies, gene therapy, CAR‑T
Pharmacokinetics
What the BODY does to the DRUG
Pharmacodynamics
What the DRUG does to the BODY
What is a poultice?
Warm herbal mass applied to skin
Poultice in medieval times was primarily used to
Draw out infection or reduce inflammation
What is a decoction?
Boiled plant extract
What is a tincture?
Alcohol‑based herbal extract
What is an electuary?
Sweet herbal paste
Ancient dosage forms
Poultices, Distillate, Decoctions
What is a clyster?
Enema
Why is iodized salt important?
Prevents goiter
What food interferes with warfarin?
Vitamin K‑rich foods
Phase I trial purpose
Safety testing in healthy volunteers
Phase II trial purpose
Effectiveness in patients with disease
Phase III trial purpose
Large‑scale testing
Phase IV trial purpose
Post‑marketing surveillance
What organization regulates drugs in the UK?
MHRA
UK’s Medicines and Healthcare products Regulatory Agency
MHRA
A medieval pill was often coated in gold or silver leaf to
Ease swallowing and preserve contents
Who is considered the father of pharmaceutical compounding?
Galen, the Greek physician
Earliest pharmacies were known as
Apothecary shops
Father of botany
Theophrastus